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Christine Horvat Davey, PhD, RN, FAAN

Assistant Professor, Frances Payne Bolton School of Nursing, Frances Payne Bolton School of Nursing

Dr. Horvat Davey examines how sleep, exercise, diet, and inflammatory pathways influence healthy aging in people with HIV and other chronic conditions, integrating mixed methods and biomarker driven research.

Teaching Information

Teaching Interests

  • HIV and Aging
  • Sleep 
  • Qualitative Methods
  • Research Methods
  • Implementation Science

Research Information

Research Interests

  • Sleep health in aging populations
  • Exercise and Diet interventions
  • Neurocognitive Aging 
  • Mixed-methods and Biomarker based approaches

Research Projects

  • Relationship of Sleep, Inflammatory Markers, Neurofilament Light Chain and Neurocognitive Function in Aging People with HIV
    Role: Principal Investigator 
    Funding agency: Prentiss Brain Health Initiative (07/2024-08/2025)
  • Relationship of Insomnia, Inflammatory Markers and Neurocognitive Function in Aging People with HIV
    Role: Principal Investigator 
    Funding agency: HIV and Aging Research Consortium, HIV and Aging Pilot Award under NIA grant #R33AG067069-01 (07/2023-06/2024)
  • Relationship of Formal Exercise Interventions, Sleep, and Inflammation Markers in People Living with HIV
    Role: Principal Investigator 
    Funding agency: NIH, National Institute of Nursing Research, K23NR019744 (04/2021-03/2025)
  • Relationship of Formal Exercise Interventions and Sleep in People Living with HIV
    Role: Principal Investigator  
    Funding agency: Sigma Theta Tau International, (2020-2021)
  • Genetic Associations of Fatigue in Individuals with End Stage Renal Disease
    Role: Principal Investigator 
    Funding agency: American Nephrology Nurses Association, Research Grant (2019-2021)
  • Gene Expression Profiling of Fatigue in Individuals with End Stage Renal Disease
    Role: Principal Investigator 
    Grant number: Eleanor C. Lambertson Scholar Fund
    Funding agency: American Nurses Foundation, Eleanor C. Lambertson Scholar Fund (2018-2019)
  • Building Family Caregiver Skills Using a Simulation-Based Intervention for Care of Patients with Cancer (Extension Project)
    PI: Susan Mazanc, PhD, RN, AOCN, FAAN
    Role: Co-Investigator
    Grant number: R37 CA240707    
    Funding Agency: NIH, National Cancer Institute,  R37 CA240707 (7/1/2023 – 6/30/2025)
  • The Influence of Habitual Physical Activity and Diet in the Development of Sarcopenia Among Older Adults With HIV
    PI: Vitor Oliveira, PhD
    Role: Co-Investigator/Site PI
    Funding agency: NIH, National Institute of Aging, 1R21AG082537-01 (4/2023 – 12/2024)
  • Impact of Physical Activity Routines and Dietary Intake on the Longitudinal Symptom Experience of People Living with HIV (PROSPER-HIV)
    MPI: Allison R. Webel, PhD, RN, FAAN and Amanda L. Willig, PhD, RD
    Role: Co-Investigator/Site PI
    Funding agency: NIH, National Institute of Nursing Research, R01NR018391 (9/2018-6/2024)

Awards and Honors

American Academy of Nursing Fellow
2025
American Academy of Nursing
Nephrology Nurse Research Award
2024
American Nephrology Nurses Association
New Investigator Award
2024
Midwest Nursing Research Society Symptom Science RIIG
New Investigator Award
2022
Midwest Nursing Research Society Self-Care RIIG
IAS Conference Scholarship
2021
International AIDS Society
Dean’s Legacy Award
2020
Frances Payne Bolton School of Nursing
Research Abstract Award
2020
American Nephrology Nurses Association
New Author Writing Award
2020
Nephrology Nursing Journal
2nd place PhD poster competition
2020
Midwest Nursing Research Society
Nurse Leader Scholar
2016
Jonas Philanthropies
Leadership Award
2010
Sigma Theta Tau, Zeta Theta Chapter

Publications

Selected Publications (Note.*Data-driven publications; ϯ Synthesis publications; ^
International publications)

*^Horvat Davey, C., Wilson, M. P., dos Santos, A., Oliveira, V. H. F., Khuu, V., Jankowski, C. M., Kulik, G. L., Iriarte Parra, E., Cook, P., Ghosh, D., MaWhinney, S., Erlandson, K. M., & Webel, A. R. (2026). Effects on fatigue and energy among older adults with HIV using high-intensity interval training versus continuous moderate intensity exercise. Nursing Research. 

*^Ruderman, S., Horvat Davey, C., Oliveira, V. H. F., Crane, H. M., Buford, T. W., Gripshover, B. M., Burkholder, G. A., Fleming, J. G., Delaney, J. A., Saag, M. S., Willig, A. L., & Webel, A. R. (2026). Higher steps per day and better diet quality associated
with lower symptom burden in adults with HIV: Results from the PROSPER HIV Study. Research Connections, vmag109. https://doi.org/10.1093/rescon/vmag109 

*^Smothers, C. G., Gandhi, S. A., Chang, J. H., Tahir, S. M., Kelley, J., Wang, E., Fareed, K., Mack, H., Dong, C., Witort, M., Armentrout, B. L., Crawford, D., Wang, J., Williams, K., Budg, Z., Horvat Davey, C., Winkelman, C., Martha, S. R., Schrock, J. W., Ardelt, A. A., & O’Connell, G. C. (2026). Systematic review and meta-analysis of stroke blood biomarker data highlights need for more translational research methods. Nature Communications. https://doi.org/10.1038/s41467-026-71329-8 

*Lal, T., Kathardekar, A., Horvat Davey, C., Boutros, C., Chakraborty, N. N., Koopman Gonzalez, S. J., Rothermel, L. D., Winter, J., & Hoehn, R. S. (2026). Who bears the burden? Provider perspectives on barriers to gastrointestinal cancer care. The
American Journal of Surgery, 256, 116926. https://doi.org/10.1016/j.amjsurg.2026.116926

*Wang, T., Chen, J., Lin, C.-C., Cuca, Y. P., Apiruknapanond, P., Shaibu, S., Canaval- Erazo, G. E., Iwu, E., Sabone, M., Makhado, L., Corless, I., Horvat Davey, C., Santa Maria, D., Schnall, R., Chen, W.-T., Solís-Báez, S., Phillips, J. C., & Dawson-Rose, C. S. (2026). A post-pandemic assessment of COVID-19 prevention disparities among people living with HIV: A multi-site international study. Journal of the Association of Nurses in AIDS Care, 37(3), 337-350. https://doi.org/10.1097/JNC.0000000000000639 

*^ Awad, J., Sun, W., Santa Maria, D., Schnall, R., Apiruknapanond, P., Wang, T., Valencia, C. P., Horvat Davey, C., Solis Baez, S., Iwu, E., Sabone, M., Makhado, L., Cuca, Y. P., Phillips, J. C., Corless, I. B., Shaibu, S., Dawson-Rose, C., & Chen, W.T.
(2026). Mental health and ART adherence in a multisite international study: The mediating roles of social support and substance use in people with HIV. AIDS and Behavior. https://doi.org/10.1007/s10461-025-04944-z 

*^ dos Santos, A. P., Oliveira, V. H. F., Willig, A. L., Ruderman, S. A., Horvat Davey, C., Buford, T. W., Long, D. M., Gripshover, B., Katundu, M., Crane, H. M., Fleming, J., Burkholder, G., Saag, M. S., & Webel, A. R. (2026). Influence of the Low-Frequency Extension Filter on Accelerometer-Based Activity Measurements in People with HIV: A Comparative Analysis. AIDS, 40(3), 394- 401. https://doi.org/10.1097/QAD.0000000000004391 

*^ Kulik, G.L., Oliveira, V.H,.F., Wilson, M.P., Khuu, V., Jankowski, C.M., Iriarte, E., Davey, C.H., Cook, P.F., Ghosh, D., Mawhinney, S., Webel, A.R., Erlandson, K.M. (2026). Comparing the Effectiveness of High Intensity Interval Training vs. Continuous Moderate Intensity Exercise on Physical Function Among Older Adults with HIV: Results from the HEALTH Trial. Open Forum Infectious Diseases. https://doi.org/10.1093/ofid/ofag002

*^Horvat Davey, C., Dawson-Rose, C., Nokes, K., Corless, I. B., Shaibu, S., Chen, W.- T., Santa Maria, D., Schnall, R., Apiruknapanond, P., Wang, T., Valencia, C., Solís Báez, S., Iwu, E., Lekone, L., Makhado, L., Cuca, Y., & Phillps, J. C. (2025). Sleep quality and disturbance during the COVID-19 pandemic among people with HIV globally:
Associations with social determinants of health. AIDS. https://doi.org/10.1097/QAD.0000000000004417

* Nokes, K. M., Horvat Davey, C., Sokhela, D. G., Orton, P. M., Phillips, J. C., Tufts, K. A., Perazzo, J. D., Chaiphibalsarisdi, P., Portillo, C., Schnall, R., Seifek, E., Hamilton, M. J., Dawson-Rose, C., & Webel, A. R. (2025). Examining hand-grip strength in persons living with HIV in United States, Thailand and South Africa: A cross-sectional study. Journal of the Association of Nurses in AIDS Care. https://doi.org/10.1097/JNC.0000000000000603

*^ Dawson-Rose, C., Horvat Davey, C., Huang, E., Cox, L., Phillips, J.C., Sabone, M., Makhado, L., Iwu, E., Fitch, K., Shaibu, S., Santa Maria, D., Schnall, R., Apiruknapanond, P., Wang, T., Sierra Perez, A.J., de Jesus Espinosa, T., Broussard, J., Cuca, Y. (2025). Impact of COVID-19 Pandemic on Quality of life, Anxiety, Connections to Friends, and Access to Resources Among People with HIV: Using the Social Ecological Model. AIDS and Behavior. https://doi.org/10.1007/s10461-025-04928-z 

*Horvat Davey, C., Willig, A. L., Ruderman, S. A., dos Santos, A. P., Oliveira, V., Gripshover, B. M., Long, D. M., Cleveland, J. D., Crane, H. M., Fleming, J., Buford, T. W., Burkholder, G., Saag, M. S., & Webel, A. R. (2025). Exploring the Relationship Between Insomnia and Biological Factors, Substance Use, and Physical Activity in People with HIV in the United States: Insights from the PROSPER Study. Journal of the Association of Nurses in AIDS Care. http:// 10.1097/JNC.0000000000000589 

*Webel, A. R., Santos, A. P., Davey, C. H., Oliveira, V., Cleveland, D., Buford, T. W., Burkholder, G., Crane, H. M., Fleming, J., & Willig, A. L. (2025). Differences in physical activity, physical function, and diet intake in men and women living with HIV in the
United States: A cross-sectional study. Journal of the Association of Nurses in AIDS Care. https://doi.org/10.1097/JNC.0000000000000571 

*^ Opara, C.C., Horvat Davey, C., Kityo, C., Brinza, E., Nazzindah, R., Bittencourt, S.M., Oliveria, V., Webel, A.R., and Longenecker, C.T. (2025). Objectively Measured Physical Activity among People with and without HIV in Uganda: Associations With Cardiovascular Risk and Coronary Artery Disease. Global Heart, 20(1), 13. https://doi.org/10.5334/gh.1398 

*^ Horvat Davey, C., Duwadi, D., Phillips, J.C., Dawson-Rose, C., Nokes, K., Perazzo, J., Schnall, R., Orton, P., Hamilton, M.J., Musanti, R., Admas Tufts, K., Sefcik, E., and Webel, A.R. (2024). Impact of Body Mass Index and VO2 Max on Symptoms, Physical Activity, and Physical Function in a Multinational Sample of People with HIV. AIDS and Behavior. https://doi.org/10.1007/s10461-024-04509-6 

*^Horvat Davey, C., Griggs, S., Duwadi, D., Martin, S., and Hickman, R.L. (2024). Mental Health, Substance Use, and a Composite of Sleep Health in Adults, 2018 Ohio Behavioral Risk Factor Surveillance System. Sleep Medicine. https://doi.org/10.1016/j.sleep.2024.09.010

*Griggs, S., Armentrout, B.L., Horvat Davey, C., & Hickman, R.L. (2024). A sleep health composite and diabetes symptom burden in young adults with type 1 diabetes. Western Journal of Nursing Research. https://doi.org/10.1177/019394592412874 

* Ruderman, S.A., Willig, A.L., Cleveland, J.D., Burkholder, G., Horvat Davey, C., Fleming, J., Gripshover, B., Katundu, M., Buford, T.W., Jones, R., Saag, M.S., Delaney, J.A.C., Crane, H.M., and Webel, A.R. (2024). Low food security is associated with frailty status and frailty components among people with HIV. AIDS (London, England). https://doi.org/10.1097/QAD.0000000000004006 

ϯ Cuca, Y. P., Horvat Davey, C., Corless, I. B., Phillips, J. C., Sierra-Perez, Á. J., Solís Báez, S., Iwu, E., Sabone, M., Mulaudzi, M. T., Murphey, C., Shaibu, S., Chen, W. T., Santa Maria, D., Schnall, R., Palmieri, P., Apiruknapanond, P., Wang, T., de Jesús, T.,
Huang, E., Broussard, J., … Dawson-Rose, C. (2024). The Social, Mental, and Physical Health Impacts of the COVID-19 Pandemic on People With HIV: Protocol of an Observational International Multisite Study. Journal of the Association of Nurses in AIDS Care: JANAC, 35(1), 60–74. https://doi.org/10.1097/JNC.0000000000000444

*Fazeli, P.L., Davey, C.H., Webel, A.R., Oliveira, V., Buford, T.W., Vance, D.E., Burkholder, G., Crane, H.M., Fleming, J., & Willig, A.L. (2024). Select dietary components are associated with better global cognition in adults with HIV. Journal of the
Association of Nurses in AIDS Care, 35(5). https://doi.org/10.1097/JNC.0000000000000479 

*Horvat Davey, C., Navis, B., Webel, A.R., Jankowski, C.M., Oliveira, V., Khuu, V., Cook, P., and Erlandson, K.M. (2023). Impact of Food Insecurity and Undernutrition on Frailty and Physical Functioning in Aging People with HIV. Journal of the Association of
Nurses in AIDS Care: JANAC. http://dx.doi.org/10.1097/JNC.0000000000000395

*^Horvat Davey, C., Longenecker, C.T., Brinza, E., McCabe, M., Hileman, C.O., Vedanthan, R., Bosworth, H.B., and Webel, A.R. (2023). The Impact of COVID-19 on Cardiovascular Health Behaviors in People Living with HIV. AIDS Care, 35(12), 1911-
1918. https://doi.org/10.1080/09540121.2023.2175195 

*^Griggs, S., Horvat Davey, C., Howard, Q., Pignatiello, G., & Duwadi, D. (2022). Socioeconomic Deprivation, Sleep Duration, and Mental Health during the First Year of the COVID-19 Pandemic. International Journal of Environmental Research and Public Health. https://doi.org/10.3390/ijerph192114367

*^ Fazeli, P.L., Willig, A.L., Oliveira, V., Buford, T.W., Vance, D.E., Burkholder, G., Crane, H.M., Davey, C.H., Fleming, J., & Webel, A.R. (2022). The association between objectively measured physical activity and cognitive functioning in middle-aged and
older people living with HIV.  AIDS and Behavior. https://doi.org/10.1007/s10461-022-03857-5 

*Davey, C. H., Trinh, V., Schexnayder, J., Longenecker, C. T., & Webel, A. (2022). Comparison of diet, muscle strength, steps per day and symptoms in people with HIV and HIV-negative peers. Research in Nursing & Health, 1–11. https://doi.org/10.1002/nur.22202 

*Davey, C.H., Webel, A.R., Sehgal, A.R. Voss, J., Hsiao, C.P., Darrah, R., Litman, P., Perez, F., and Desai, N. (2020). Genetic Correlates of Patient-Reported Fatigue in Individuals with End Stage Renal Disease. Western Journal of Nursing Research,
42(12), 1042-1049. https://doi.org/10.1177/0193945920919911

*Horvat Davey, C., Perazzo, J. D., Vest, M., Josephson, R. A., Oliveira, V., Sattar, A., & Webel, A. R. (2020). The relationship of cardiorespiratory function, fatigue and depressive symptoms in PLHIV. AIDS care, 32(7), 877–881. https://doi.org/10.1080/09540121.2019.1659920

*Gunzler, D., Sehgal, A., Kauffman, K., Horvat Davey, C., Dolata, J., Figueroa, M., Huml, A., Pencak, J., and Sajatovic, M. (2020). Identifying Depression Phenotypes by Applying RDoC Domains to the PHQ-9. Psychiatry Research. https://doi.org/10.1016/j.psychres.2020.112872

ϯ Horvat Davey, C., Webel, A.R., Sehgal, A.R., Voss, J.G., & Huml, A.M. (2019). Fatigue in Individuals with End Stage Renal Disease. Nephrology Nursing Journal, 46(5), 497-508. PMID: 31566345

*Perazzo, J. D., Currie, J., Horvat Davey, C., Lambert, J., & Webel, A. R. (2019). Depression and Social Capital in People Living with HIV. Journal of Psychiatric and Mental Health Nursing, 27(1), 54-61. https://doi.org.10.1111/jpm.12552

ϯ Horvat Davey, C., Dolansky, M.A., Harris, A.T., & Singh, M.K. (2019). Integrating a Reflective Learning Activity to Ensure Quality Improvement Project Success. Nursing Education Perspectives. https://doi.org.10.1097/01.NEP.0000000000000610 

Education

Doctor of Nursing Science
Case Western Reserve University
2019
Bachelor of Science in Nursing
The University of Toledo
2010
Bachelor of Science in Pharmaceutical Sciences
The University of Toledo
2008

Residencies, Internships and Fellowships

NIDDK Clinical Methods for Nutrition and Obesity Research Course, Fellow
National Institutes of Health (NIH)
2025
ORBIT Institute: Developing Behavioral Treatments to Improve Health (NIH short course), Fellow
National Institutes of Health (NIH)
2024
VA National Quality Scholars Fellowship, Predoctoral Fellow
Cleveland VA Medical Center
2019