Santosh Ghosh, PhD

Biological Sciences
School of Dental Medicine

Research Information

Research Interests

Research Interests
 Antimicrobial Peptides
 Immunology 
 Proteomics 
 Bioinformatics
 Microbiology
 Cancer Biomarker
 COVID-19


Full List:

Zhang L, Ghosh SK, Basavarajappa SC, Chen Y, Shrestha P, Penfield J, Brewer A,
Ramakrishnan P, Buck M, Weinberg A. HBD-2 binds SARS-CoV-2 RBD and blocks viral entry:
Strategy to combat COVID-19. iScience. 2022 Mar 18;25(3):103856. doi:10.1016/j.isci.2022.103856. Epub 2022 Feb 2. PMID: 35128350; PMCID: PMC8808565.

Ghosh SK, Weinberg A. Ramping Up Antimicrobial Peptides Against Severe Acute Respiratory
Syndrome Coronavirus-2. Front Mol Biosci. 2021 Jun 21;8:620806. doi:
10.3389/fmolb.2021.620806. PMID: 34235176; PMCID: PMC8255374.

Ghosh SK, McCormick TS, Weinberg A. Human Beta Defensins and Cancer: Contradictions
and Common Ground. Front Oncol. 2019 May 3;9:341. doi: 10.3389/fonc.2019.00341. PMID:
31131258; PMCID: PMC6509205.

Ghosh SK, Feng Z, Fujioka H, Lux R, McCormick TS, Weinberg A. Conceptual Perspectives:
Bacterial Antimicrobial Peptide Induction as a Novel Strategy for Symbiosis with the Human
Host. Front Microbiol. 2018 Feb 26;9:302. doi: 10.3389/fmicb.2018.00302. PMID: 29535688;
PMCID: PMC5835341.

Bhaskaran N, Ghosh SK, Yu X, Qin S, Weinberg A, Pandiyan P, Ye F. Kaposi's sarcoma-
associated herpesvirus infection promotes differentiation and polarization of monocytes into
tumor-associated macrophages. Cell Cycle. 2017;16(17):1611-1621. doi:
10.1080/15384101.2017.1356509. Epub 2017 Jul 27. PMID: 28750175; PMCID: PMC5587027.

Sutton MT, Fletcher D, Ghosh SK, Weinberg A, van Heeckeren R, Kaur S, Sadeghi Z, Hijaz A,
Reese J, Lazarus HM, Lennon DP, Caplan AI, Bonfield TL. Antimicrobial Properties of
Mesenchymal Stem Cells: Therapeutic Potential for Cystic Fibrosis Infection, and Treatment.
Stem Cells Int. 2016;2016:5303048. doi: 10.1155/2016/5303048. Epub 2016 Jan 26. PMID:
26925108; PMCID: PMC4746399.

Ghosh SK, McCormick TS, Eapen BL, Yohannes E, Chance MR, Weinberg A. Comparison of
epigenetic profiles of human oral epithelial cells from HIV-positive (on HAART) and HIV-
negative subjects. Epigenetics. 2013 Jul;8(7):703-9. doi: 10.4161/epi.25028. Epub 2013 May
17. PMID: 23804146; PMCID: PMC3781189.

Ghosh SK, Yohannes E, Bebek G, Weinberg A, Jiang B, Willard B, Chance MR, Kinter MT,
McCormick TS. Proteomic and bioinformatic profile of primary human oral epithelial cells. J
Proteome Res. 2012 Nov 2;11(11):5492-502. doi: 10.1021/pr3007254. Epub 2012 Oct 16.
PMID: 23035736; PMCID: PMC3508721.

Ghosh SK, Gupta S, Jiang B, Weinberg A. Fusobacterium nucleatum and human beta-
defensins modulate the release of antimicrobial chemokine CCL20/macrophage inflammatory
protein 3α. Infect Immun. 2011 Nov;79(11):4578-87. doi: 10.1128/IAI.05586-11. Epub 2011
Sep 12. PMID: 21911466; PMCID: PMC3257922.

Gupta S, Ghosh SK, Scott ME, Bainbridge B, Jiang B, Lamont RJ, McCormick TS, Weinberg A.
Fusobacterium nucleatum-associated beta-defensin inducer (FAD-I): identification, isolation,
and functional evaluation. J Biol Chem. 2010 Nov 19;285(47):36523-31. doi:
10.1074/jbc.M110.133140. Epub 2010 Sep 16. PMID: 20847052; PMCID: PMC2978580.

Ghosh SK, Gerken TA, Schneider KM, Feng Z, McCormick TS, Weinberg A. Quantification of
human beta-defensin-2 and -3 in body fluids: application for studies of innate immunity. Clin
Chem. 2007 Apr;53(4):757-65. doi: 10.1373/clinchem.2006.081430. Epub 2007 Feb 22. PMID:


Doctor of Philosophy
Indian Institute of Technology
Master of Science
North Bengal University

Additional Information