The Webel Research Lab created and maintains an HIV Biobehavioral Data Repository which stores de-identified demographic, behavioral, psychosocial, structural, medical chart abstraction, biological data, and frozen specimens in more than 300 adults living with HIV over 6 waves of data collection. To help advance science, we have recently added approximately 100 well-matched HIV uninfected adults to the Data Repository.
New participants are added regularly and we welcome collaborations with new investigators to answer important HIV-related research questions.
|Data Elements Contained in the HIV Biobehavioral Data Repository|
HIV-specific biomarkers (CD4+ T cell count, HIV-Viral RNA);
Inflammatory biomarkers (e.g., IL-6, hsCRP), cardiovascular biomarkers (fasting lipid panel, insulin resistance, Coronary Calcium Scoring, waist-hip-ratio, BMI), maximal cardiopulmonary exercise tests, functional MRI, vascular reactivity
|Imaging||Coronary Computer Tomography Scan, pericardial and liver fat quality and quantity; fMRI of the brain|
|Psychological / Neurological||
Depression, Cognitive Function, Attention, Cardiovascular Disease Risk Perception, Decision-making and Risk, Response Time, Self-efficacy;
Perception of Risk
|Behavioral||Physical Activity (actigraphy, activity recall), Sleep (actigraph and PROMIS), Medication Adherence, Substance Use (tobacco, alcohol, and illicit drug use), Self-Management|
|Symptoms||Depression, Anxiety, Fatigue|
|Functional||Six Minute Walk Test, Hand-Grip Dynamometry, Flexibility|
|Psychosocial||Social Capital, HIV Stigma|
|Ecological||Weather, Neighborhood Environment, Food Security|
Details on the history and methods employed in developing our data repository can be found in our recent article: Perazzo, J.D., Rodriguez, M., Currie, J., Salata, R., & Webel, A.R. (2018). Creation of data repositories to advance nursing science. Research in Nursing and Health. PMID 29277149
Current studies that have contributed data to the HIV Biobehavioral Data Repository are found in the table below.
HIV Bio-behavioral Research Office Protocols
|Protocol||Principal Investigator||Year(s)||(N)||Data Collection Frequency|
|Exploring relationships among stress, isolation, and physical activity in older adults living with HIV (TRIP)||Webel||2011-2013||105||Baseline and 12 Months|
|A randomized clinical trial of SystemCHANGE, a diet and exercise self-management intervention in people living with HIV (BOBCAT)||Webel||2015-2016||129 (n=109 HIV+ and n=20 HIV)||Baseline, 3, 6, 12, & 24 Months|
|Social Capital and Self-Management in Women Living with HIV||Webel||2015-2016||29||Baseline, 12 Weeks, 24 Weeks|
|An Ecological Understanding of Physical Activity Patterns of Adults Living with HIV (Active Living)||Webel||2016-2017||115||1 Visit|
|A Mixed Methods Study of Physical Activity and Diet Self-Management in People Living with HIV||Perazzo||2017||100 (n=51 HIV+ and 49 HIV-)||1 Visit|
|Perceived CVD Risk in People Living with HIV and Impact on CVD Prevention Behavior||Webel & Longenecker||2017-2018||Target 191 (n=105 HIV+ and n=86 HIV-)||1 Visit|