HIV Data Repository

Stock photo of books and laptop computer

The HIV Biobehavioral Data Repository stores de-identified demographic, behavioral, psychosocial, structural, medical chart abstraction, biological data, and frozen specimens in more than 300 adults living with HIV over 6 waves of data collection. To help advance science, we have recently added approximately 100 well-matched HIV uninfected adults to the Data Repository.

New participants are added regularly and we welcome collaborations with new investigators to answer important HIV-related research questions.

Data Elements Contained in the HIV Biobehavioral Data Repository
Domain Variables

HIV-specific biomarkers (CD4+ T cell count, HIV-Viral RNA);

Inflammatory biomarkers (e.g., IL-6, hsCRP), cardiovascular biomarkers (fasting lipid panel, insulin resistance, Coronary Calcium Scoring, waist-hip-ratio, BMI), maximal cardiopulmonary exercise tests, functional MRI, vascular reactivity

Imaging Coronary Computer Tomography Scan, pericardial and liver fat quality and quantity; fMRI of the brain
Psychological / Neurological

Depression, Cognitive Function, Attention, Cardiovascular Disease Risk Perception, Decision-making and Risk, Response Time, Self-efficacy;

Perception of Risk

Behavioral Physical Activity (actigraphy, activity recall), Sleep (actigraph and PROMIS), Medication Adherence, Substance Use (tobacco, alcohol, and illicit drug use), Self-Management
Symptoms Depression, Anxiety, Fatigue
Functional Six Minute Walk Test, Hand-Grip Dynamometry, Flexibility
Psychosocial Social Capital, HIV Stigma
Ecological Weather, Neighborhood Environment, Food Security

Details on the history and methods employed in developing our data repository can be found in our recent article: Perazzo, J.D., Rodriguez, M., Currie, J., Salata, R., & Webel, A.R. (2018). Creation of data repositories to advance nursing science. Research in Nursing and Health. PMID 29277149

Current studies that have contributed data to the HIV Biobehavioral Data Repository are found in the table below.

HIV Bio-behavioral Research Office Protocols

Protocol Principal Investigator Year(s) (N) Data Collection Frequency
Exploring relationships among stress, isolation, and physical activity in older adults living with HIV (TRIP) Webel 2011-2013 105 Baseline and 12 Months
A randomized clinical trial of SystemCHANGE, a diet and exercise self-management intervention in people living with HIV (BOBCAT) Webel 2015-2016 129 (n=109 HIV+ and n=20 HIV) Baseline, 3, 6, 12, & 24 Months
Social Capital and Self-Management in Women Living with HIV Webel 2015-2016 29 Baseline, 12 Weeks, 24 Weeks
An Ecological Understanding of Physical Activity Patterns of Adults Living with HIV (Active Living) Webel 2016-2017 115 1 Visit
A Mixed Methods Study of Physical Activity and Diet Self-Management in People Living with HIV Perazzo 2017 100 (n=51 HIV+ and 49 HIV-) 1 Visit
Perceived CVD Risk in People Living with HIV and Impact on CVD Prevention Behavior Webel & Longenecker 2017-2018 Target 191 (n=105 HIV+ and n=86 HIV-) 1 Visit