Carlos Crespo, PhD

Department of Chemistry
College of Arts and Sciences
Molecular Oncology Program
Case Comprehensive Cancer Center

Research Information

Research Interests

The Crespo research group focuses on probing and understanding light-induced phenomena in molecules and polymers in solution with primary applications in photodynamic therapy and photosensitizers. There are two major areas of ongoing investigations in skin-cancer related research: (1) excited-state dynamics and photochemistry of DNA/RNA monomers and polymers; and (2) design and study of modified DNA and RNA sensitizers for photodynamic and photo crosslinking applications. Our group uses analytical instrumentation and time-resolved spectroscopic techniques to produce specific knowledge of the factors controlling these photochemical processes. The experimental work is complemented with ground- and excited-state electronic-structure computations.