Small Molecule Drug Development

The mission of the Small Molecule Drug Development Shared Resource (SR) is to optimize robust assays in 384-well format and to screen large chemical libraries to identify new small molecules for innovative cancer therapeutics. 

Service

Service/Expertise Cost Description
Initial consultation None Investigators receive feedback regarding assay development/HTS goals, while Director and Managing Director suggest optimal assay approaches
Facility orientation/training $200/ session 2-hr session covering all instruments 
Operetta microscope, hourly usage $40/hour Enables investigators to benefit from automated 
Managing Director support $100/hour General support in assay development and execution
Bioactives Library access (3,200 cpds) $200 Enables pilot screening
HTS Library access (50,000 molecules) $2,000 Enables HTS
All-inclusive screening packages Quotes available Enables dedicated % effort from Managing Director, library access, and equipment time. Can include reagent costs. Priced on a per-project basis due to varying assay needs.

Acknowledgment

Remember to acknowledge the valuable services provided by Cancer Center Shared Resources in your research papers and publications:
"This research was supported by the Small Molecule Drug Development Shared Resource of the Case Comprehensive Cancer Center (P30CA043703)."

Contact for More Information

Director Drew Adams, PhD
216.368.4922
dja59@case.edu
Managing Director Yuriy Fedorov, PhD
216.368.1506
yuriy.fedorov@case.edu