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Effective March 19, 2020

We will continue to offer ALL of our services, but with significant changes to our User requests process, Staff Scheduling, and User self-guided operations practices.  All current research projects will continue depending on resources available and any new research projects will be initiated upon receiving and approval of a statement disclosing the critical nature of the research.

Revisions to Operating Protocol: Our modified protocol minimizes face to face interaction; we will communicate primarily by email, phone and other remote solutions with our Users.   

  • Essential personnel of our SR include 1 technical operator; to implement necessary social distancing recommendations, our operators will provide assistance by appointment only. 
  • All technical issues with instruments and servers will be resolved in a timely fashion and according to time and resource availability.
  • Self-guided user operations will continue with following changes:
    • social distancing of six feet per person and to the greatest extent possible should be implemented at all times,
    • each user is responsible for work stations cleaning and decontamination after operations complete, including bench space between instruments.

Small Molecule Drug Development

The Small Molecule Drug Development Shared Resource (SR) optimizes robust assays in 384-well format and to screen large chemical libraries to identify new small molecules for innovative cancer therapeutics. 

Services

Service/Expertise Cost Description
Initial consultation None Investigators receive feedback regarding assay development/HTS goals, while Director and Managing Director suggest optimal assay approaches
Facility orientation/training $200/ session 2-hr session covering all instruments
Operetta microscope, hourly usage $40/hour Enables investigators to benefit from automated
Managing Director support $100/hour General support in assay development and execution
Bioactives Library access (3,200 cpds) $200 Enables pilot screening
HTS Library access (50,000 molecules) $2,000 Enables HTS
All-inclusive screening packages Quotes available Enables dedicated % effort from Managing Director, library access, and equipment time. Can include reagent costs. Priced on a per-project basis due to varying assay needs.

Contact for More Information

Director: Drew Adams, PhD
216.368.4922
dja59@case.edu

Managing Director: Yuriy Fedorov, PhD
216.368.1506
yuriy.fedorov@case.edu