The mission of the Small Molecule Drug Development Shared Resource (SR) is to optimize robust assays in 384-well format and to screen large chemical libraries to identify new small molecules for innovative cancer therapeutics.
Service
| Service/Expertise | Cost | Description |
|---|---|---|
| Initial consultation | None | Investigators receive feedback regarding assay development/HTS goals, while Director and Managing Director suggest optimal assay approaches |
| Facility orientation/training | $200/ session | 2-hr session covering all instruments |
| Operetta microscope, hourly usage | $40/hour | Enables investigators to benefit from automated |
| Managing Director support | $100/hour | General support in assay development and execution |
| Bioactives Library access (3,200 cpds) | $200 | Enables pilot screening |
| HTS Library access (50,000 molecules) | $2,000 | Enables HTS |
| All-inclusive screening packages | Quotes available | Enables dedicated % effort from Managing Director, library access, and equipment time. Can include reagent costs. Priced on a per-project basis due to varying assay needs. |
Acknowledgment
Remember to acknowledge the valuable services provided by Cancer Center Shared Resources in your research papers and publications:
"This research was supported by the Small Molecule Drug Development Shared Resource of the Case Comprehensive Cancer Center (P30CA043703)."
Contact for More Information
| Director | Drew Adams, PhD 216.368.4922 dja59@case.edu |
| Managing Director | Yuriy Fedorov, PhD 216.368.1506 yuriy.fedorov@case.edu |