Jason Brown, MD, PhD

Assistant Professor
Hematology and Oncology
University Hospitals Seidman Cancer Center
Developmental Therapeutics Program
Case Comprehensive Cancer Center

I am a medical oncologist, specializing in treatment of genitourinary cancers. I am the medical oncology lead for urothelial cancer at the Seidman Cancer Center. I aim to develop and run clinical trials for these patients as well as to discover and validate clinically relevant biomarkers to optimize the right treatment for the right patients. My clinical and scientific background helps me understand the clinical challenges that are unique to this field. I plan on fostering collaboration with laboratory colleagues, and my prior laboratory experience will be an asset in these relationships. I have prior research background with immune predictive biomarkers. I conducted my predoctoral research with Dr. David Rimm. I developed and validated a novel method for quantifying tumor infiltrating lymphocytes in breast cancer tissue. I further gained experience on clinical investigation with scientific correlation while investigating metformin as a cancer stem cell agent in ovarian cancer. I further worked on biomarker development during my postdoctoral research with Dr. Arul Chinnaiyan on cancer-specific circular RNA during my oncology fellowship. As a junior faculty member, I seek to build upon this foundation and develop an independently funded research program focusing on biomarkers in genitourinary malignancies and early phase clinical trials with strong correlatives.