Lerner Research Institute, Cleveland Clinic
Immune Oncology Program
Case Comprehensive Cancer Center
The overarching goal of our lab is to gain key molecular insights into innate immune regulations in tumor microenvironment (TME), with a goal of harnessing innate immunity to remodel the TME for better cancer immunotherapy. Currently we mainly focus on understanding the molecular regulation of cGAS-STING signaling in cancer cell and in T cells, and how they shape antitumor immune response.