Raymond F. Muzic, Jr., PhD

Department of Radiology
School of Medicine
Department of Biomedical Engineering
Case School of Engineering
Scientific Director
Quantitative Imaging Laboratory
School of Medicine
Cancer Imaging Program
Case Comprehensive Cancer Center

Research Information

Research Interests

  • Quantitative imaging, analysis and modeling, optimal experiment design
  • Metabolic imaging
  • Cancer imaging
  • Cardiovascular imaging

Dr. Muzic's research spans multiple therapeutic areas including cancer, cardiac, and diabetes research. His research works includes quantitative analysis of biomedical imaging data, physiologic modeling, optimal experiment design, assessment of new radiopharmaceuticals, imaging response to therapy, and in vivo quantification of receptor concentration. His work also includes creation and dissemination of COMKAT software for quantitative analysis of biomedical image data, and is used to support research and teaching.

Dr. Muzic is the Scientific Director of the Quantitative Imaging Laboratory

Awards and Honors

Teacher of the Year, Radiologic Physics
University Hospitals Case Medical Center
Teacher of the Year, Non-interpretive skills
University Hospitals Case Medical Center Department of Radiology
Engineer of the Year
Institute of Electrical and Electronics Engineers (IEEE) Cleveland Section
Graduated with Highest Honors
Case Western Reserve University


View All Publications

Liang, F; Qian, P; Su KH; Baydoun A; Leisser A; Van Hedent S; Kuo JW; Zhao K; Parikh P; Lu Y; Traughber BJ; Muzic RF Jr. Abdominal, multi-organ, auto-contouring method for online adaptive magnetic resonance guided radiotherapy: an intelligent, multi-level fusion approach. Artif Intel Med. 90:34-41, 2018. PMID: 30054121. DOI: 10.1016/j.artmed.2018.07.001.

Su KH; Kuo JW; Jordan DW; Van Hedent S; Klahr P; Wei Z; Al Helo R; Liang F; Qian P; Pereira GC; Rassouli N; Gilkeson RC; Traughber BJ; Cheng CW; Muzic RF. Machine learning-based dual-energy CT parametric mapping. Phys Med Biol. 63(12):125001, 2018. PMID: 29787382. DOI: 10.1088/1361-6560/aac711.

Traughber BJ; Kotys MS; Muzic RF. MRI method for assessing individual pixels or voxels tissue-specific PET attenuation values. US Patent 9,536,303. 2014.

Hu L; Su KH; Pereira GC; Grover A; Traughber B; Traughber M; Muzic RF Jr. k-space sampling optimization for ultrashort TE imaging of cortical bone: applications in radiation therapy planning and MR-based PET attenuation correction. Med Phys. 41(10):102301, 2014. PMID: 25281971. DOI: 10.1118/1.4894709.

Kolthammer JA; Muzic RF. Optimized dynamic framing for PET-based myocardial blood flow estimation. Phys Med Biol. 58(16):5783-801, 2013. PMID: 23912223. DOI: 10.1088/0031-9155/58/16/5783.


Doctor of Philosophy
Case Western Reserve University
Master of Science
Case Western Reserve University
Bachelor of Science
Case Western Reserve University