My research involves integrating molecular, lifestyle and clinical epidemiology to study risk factors for initiation and progression of cancer, with the primary goal to translate research findings into direct application for primary and secondary cancer prevention. A major area of my research focus is in investigating circadian rhythm disruption as a risk factor for cancer, and particularly for risk of advanced prostate cancer. I am also interested in understanding the molecular basis for tumor progression and the clinical utility of utilizing genomic markers for cancer outcomes, with a particular focus on prostate, testicular and bladder cancer. Another area of my research focus is in developing lifestyle interventions (e.g. physical activity) to enhance the efficacy of therapeutic interventions, ameliorate treatment-related effects, and improve overall health and quality of life among cancer patients.