Mark Cameron, PhD

Associate Professor
Department of Population and Quantitative Health Sciences
School of Medicine
Center for RNA Science and Therapeutics
School of Medicine
Immune Oncology Program
Case Comprehensive Cancer Center
Cleveland Institute for Computational Biology

Dr. Mark Cameron applies genomic technologies and bioinformatic methods to identify biomarkers (immune correlates) of infectious diseases, such as HIV, and chronic inflammatory conditions, such as psoriasis. He and his team have broad computational expertise in analyzing across data types and studies, and focus their work on targets or diagnostics that can be used in specific immunotherapy or vaccine design.

Dr. Cameron also directs the genomics activities of several large cores or consortia, including the Case Western Reserve University Applied Functional Genomics Core, the Miami Center for AIDS Research (Inter-CFAR) Bioinformatics Core, the Case Western Reserve University CFAR Systems Biology Core, and the international Early Treated Perinatally Infected individuals: Improving Children’s Lives with an HIV Vaccine (EPIICAL). These collaborative cores allow Dr. Cameron to apply his systems approach and data from gene sequence, to gene transcription, to protein, cellular and antibody function, to find out what goes right or wrong in the immune systems of patients who respond variably to various diseases or treatments.

Teaching Information

Courses Taught

Current Issues in Genetic Epidemiology
Technologies in Bioinformatics

Research Information

Research Interests

Functional Genomics & Single Cell Biology 
Biomarkers of Acute & Chronic Disease
Interferome & Inflammasome

Professional Memberships

American Association of Immunologists
American Society for Virology
Society for Investigative Dermatology

External Appointments

Cleveland Institute for Computational Biology


Find Dr. Cameron's publications here

Editorial roles:

  • The Journal of infection in Developing Countries, Editor
  • Pathogens and Immunity, Associate Editor


Microbiology and Immunology
Western University, London, Ontario
Western University, London, Ontario

Additional Information

Contributions to science:

  • Applied novel, low input, multi-omic assays and translation expertise to assess the genome and functional genome of difficult clinical samples from clinical studies and trials
  • Identified pro-inflammatory gene correlates of pathogenesis in human subjects versus animal models and mechanisms of their abatement via vaccines or therapies 
  • Identifying cell subset specific transcriptomic signatures over injury, immune system development and cell survival/differentiation for application to clinical studies

Student and mentee totals, over CWRU career:  

  • Master’s: 5 mentees
  • PhD: 3 
  • Post-doc:  2 
  • A sampling of CWRU PhD graduates’ and Postdoctoral fellows’ current careers:  
    • Nova Southeastern University, Genomics Core
    • Harvard T.H. Chan School of Public Health
    • Case Western Reserve University