Advance the scientific rigor and validity of your research with the CTSC’s comprehensive biostatistical, epidemiological, and study design resources. Through our specialized cores and partnerships—including the Biomedical Informatics and Data Science (BIDS) team and the Department of Population & Quantitative Health Sciences (PQHS)—investigators can access expert guidance throughout the entire research lifecycle. Whether you are defining early study protocols, navigating complex population-based databases, or requiring advanced multi-omics analytics for cancer research, our team provides the tailored methodological support, predictive modeling, and grant-review expertise necessary to elevate your discoveries from concept to publication. To support your project needs, we provide specialized consultation and resources across four core areas:
BIDS biostatisticians are available for consultation throughout the research lifecycle — from initial study design through analysis and manuscript preparation.
Services include:
• Study design consultation (sample size calculation, randomization, blinding)
• Statistical analysis plan development
• Selection and application of appropriate statistical methods
• Longitudinal and survival analysis
• Multilevel and mixed-effects modeling
• Machine learning and predictive modeling for clinical research
• Review of statistical sections in grant applications and manuscripts
BIDS provides guidance on study design for observational, interventional, and mixed-methods research. This includes advice on:
• Selection of appropriate study designs (RCTs, cohort, case-control, cross-sectional)
• Causal inference and confounding control
• Population-based database research
• Integration of electronic health record data with primary research data
Through the Department of Population & Quantitative Health Sciences (PQHS), investigators may access a range of population-based databases for outcomes and epidemiological research:
• Ohio Medicaid enrollment and claims data
• National Inpatient Sample (NIS) and State Inpatient Databases (SID)
• The Health and Retirement Study
• Cancer Aging Linked Database
• Linked Ohio Department of Mental Health and death certificate data
BIDS staff can advise on data source selection, data use agreements, IRB considerations, and provide analytic support for studies using these resources. Visit the Department of Population & Quantitative Health Sciences.
For investigators affiliated with the Case Comprehensive Cancer Center, the BBCF provides statistical, bioinformatics, and clinical informatics research support, including assistance with microarray data and next-generation sequencing analysis.
Learn more: https://case.edu/cancer/research/shared-resources/biostatistics-and-bioinformatics