Horst A. von Recum, PhD

Executive Vice Chair
Case School of Engineering
Professor
Department of Biomedical Engineering
Case School of Engineering
School of Medicine
Member
Cancer Imaging Program
Case Comprehensive Cancer Center

Research Information

Research Interests

The research in our laboratory focuses on novel platforms for the delivery of molecules and cells. In the molecular delivery projects we are examining novel affinity-based systems for delivery of therapeutic agents for HIV therapies, wound dressings, ocular disease,  localized chemotherapy and other applications. Affinity-based delivery uses molecular interactions to control the rate of release beyond that capable by other means such as diffusion and degradation.  This allows for control of delivery to better match the physiological need of the drug.

The cellular delivery projects are examining using directed differentiation to produce tissue engineered constructs from stem cell sources. Stem cells show great promise as a therapeutic tool due to their  unlimited replication potential and their plasticity, or capacity to become many different cell types. Better control of differentiation and selection, will allow for rapid expansion of high purity differentiated cells suitable for tissue engineering, toxicology and pharmacology, as well as cellular modeling, without the need for isolating cells from primary sources.

Publications

View full list of publications.

Additional Information

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