Great Lakes Breast Cancer Symposium Agenda | Case Comprehensive Cancer Center

Monday, October 25, 2021
10:00-10:15am	"Welcome" Stan Gerson, MD Dean, School of Medicine Director, Case Comprehensive Cancer Center, Case Western Reserve University Halle Moore, MD Case Comprehensive Cancer Center, Cleveland Clinic Ruth Keri, PhD Case Comprehensive Cancer Center, Cleveland Clinic
10:15-11:50	SESSION I: Therapeutics: Response and Resistance "Targeting HR-proficient Triple-negative Cancer Cells with a Novel RAD51 Inhibitor" Carola Neumann, MD University of Pittsburgh "Tolerable Strategies to Overcome Treatment Resistance in Breast Cancer" Mathew Cherian, MBBS The Ohio State University "Predictive Gene Regulatory Models" Hatice Osmanbeyoglu, PhD University of Pittsburgh "Radiomics and Pathomics for Breast Cancer Risk Stratification and Disease Progression" Anant Madabhushi, PhD Case Comprehensive Cancer Center, Case Western Reserve University Q&A panel discussion
11:50am-12:20pm	Lunch
12:20-1:55	SESSION II: Survivorship and Disparities "Quality of Life After Chemotherapy: Social Influences and Biological Mechanisms Discovered Through Mouse Research" Courtney DeVries, PhD West Virginia University "'The Wednesday Meeting': Collaborations to improve the care of patients with Metastatic Breast Cancer Peg Rosenzweig, PhD, CRNP-C, AOCNP University of Pittsburgh "Cancer-related Fatigue in Early-stage Breast Cancer Patients" Emidio E. Pistilli, MS, PhD West Virginia University "Exercise Benefit in Older Breast Cancer Survivors from Diverse Racial and SES Backgrounds" Cynthia Owusu, MD Case Comprehensive Cancer Center, University Hospitals Q&A panel discussion
1:55-2:05	Break
2:05-3:05	Networking Session
3:05-4:40	SESSION III: Microenvironment and Immunology "Determining the Formula for Anti-tumor Tertiary Lymphoid Structure Formation in Cancer Patients" Tullia Bruno, PhD University of Pittsburgh "Role of Tumor Macrophage Populations in Regulating Hypoxia and Immunosuppression in Breast Cancer" Tim Eubank, PhD West Virginia University "TME-mediated Signaling Mechanisms in Breast Cancer Progression and Metastasis" Ramesh Ganju, PhD The Ohio State University "Targeted Immuno-Nanoparticles for Directing Antitumor Immune Response Against Breast Cancer Metastasis" Efstathios Karathanasis, PhD Case Comprehensive Cancer Center, Case Western Reserve University Q&A panel discussion
4:40-4:50	Closing remarks

Tuesday, October 26, 2021
8:00-8:05am	"Welcome" Ruth Keri, PhD Case Comprehensive Cancer Center, Cleveland Clinic Halle Moore, MD Case Comprehensive Cancer Center, Cleveland Clinic
8:05-9:40	SESSION IV: Cancer Cell Biology "Targeting small G Proteins in TNBC" Steve Sizemore, PhD The Ohio State University "Data-driven Learning: How oncogenic gene expression locally alters heterocellular networks" David J. Klinke II, PhD West Virginia University "Association of Germline Variants with Somatic TP53 and PIK3CA Mutations in Breast Cancer" Amanda Toland, PhD The Ohio State University "Filament Formation by Metabolic Enzymes: A new twist on breast cancer metabolism" Bradley Webb, PhD West Virginia University Q&A panel discussion
9:40-9:50	Break
9:50-10:50	Poster Session
10:50-11:00	Break
11:00am-12:00pm	"Keynote Presentation: "Tackling Resistance in Triple-negative Breast Cancer" Helen Piwnica-Worms, PhD The University of Texas MD Anderson Cancer Center
12:00-12:30	Lunch
12:30-1:30	Patient Advocacy Session
1:30-1:40	Break
1:40-2:40	Poster Session
2:40-2:50	Break
2:50-4:25	SESSION V: Metastasis "TNBC Signaling and Drug Response Dynamics in the Metastatic Niche" Alexander Davies, DVM, PhD The Ohio State University "Neural Communication in Metastatic Progression" Jennifer Yu, MD, PhD Case Comprehensive Cancer Center, Cleveland Clinic "Targeting MRTF Signaling to Disrupt Metastatic Colonization of Breast Cancer Cells" Partha Roy, PhD University of Pittsburgh "Whole Transcriptome Profiling of Circulating Tumor Cells in Metastatic Breast Cancer" Julie Lang, MD Cleveland Clinic Q&A panel discussion
4:25-4:35	Closing remarks