Great Lakes Breast Cancer Symposium Agenda

Monday, October 25, 2021
10:00-10:15am

"Welcome"

Stan Gerson, MD
Interim Dean, School of Medicine
Director, Case Comprehensive Cancer Center, Case Western Reserve University

Halle Moore, MD
Case Comprehensive Cancer Center, Cleveland Clinic

Ruth Keri, PhD
Case Comprehensive Cancer Center, Cleveland Clinic

10:15-11:50

SESSION I: Therapeutics: Response and Resistance

"Targeting HR-proficient Triple-negative Cancer Cells with a Novel RAD51 Inhibitor"
Carola Neumann, MD
University of Pittsburgh

"Tolerable Strategies to Overcome Treatment Resistance in Breast Cancer"
Mathew Cherian, MBBS
The Ohio State University

"Predictive Gene Regulatory Models"
Hatice Osmanbeyoglu, PhD
University of Pittsburgh

"AI in Breast Cancer Imaging"
Anant Madabhushi, PhD
Case Comprehensive Cancer Center, Case Western Reserve University 

Q&A panel discussion

11:50am-12:20pm Lunch
12:20-1:55

SESSION II: Survivorship and Disparities

"Mechanisms Influencing Post-chemotherapy Quality of Life: Cognitive Impact of Breast Cancer Therapy"
Courtney DeVries, PhD
West Virginia University

"'The Wednesday Meeting': Collaborations to improve the care of patients with Metastatic Breast Cancer 
Peg Rosenzweig, PhD, CRNP-C, AOCNP
University of Pittsburgh

"Cancer-related Fatigue in Early-stage Breast Cancer Patients"
Emidio E. Pistilli, MS, PhD
West Virginia University

"Exercise Benefit in Older Breast Cancer Survivors from Diverse Racial and SES Backgrounds"
Cynthia Owusu, MD
Case Comprehensive Cancer Center, University Hospitals

Q&A panel discussion

1:55-2:05 Break
2:05-3:05 Networking Session
3:05-4:40

SESSION III: Microenvironment and Immunology

"Determining the Formula for Anti-tumor Tertiary Lymphoid Structure Formation in Cancer Patients"
Tullia Bruno, PhD
University of Pittsburgh

"Role of Tumor Macrophage Populations in Regulating Hypoxia and Immunosuppression in Breast Cancer"
Tim Eubank, PhD
West Virginia University 

"TME-mediated Signaling Mechanisms in Breast Cancer Progression and Metastasis"
Ramesh Ganju, PhD
The Ohio State University

"Combination of a Dual Agonist Immunostimulatory Nanoparticle with PD1 Blockage for Curative Neoadjuvant Immunotherapy of Metastatic Breast Cancer"
Efstathios Karathanasis, PhD
Case Comprehensive Cancer Center, Case Western Reserve University 

Q&A panel discussion

4:40-4:50 Closing remarks

 

Tuesday, October 26, 2021
8:00-8:05am

"Welcome"

Ruth Keri, PhD
Case Comprehensive Cancer Center, Cleveland Clinic

Halle Moore, MD
Case Comprehensive Cancer Center, Cleveland Clinic

8:05-9:40

SESSION IV: Cancer Cell Biology

"Targeting small GTPases in TNBC"
Steve Sizemore, PhD
The Ohio State University

"Data-driven Learning: How oncogenic gene expression locally alters heterocellular networks"
David J. Klinke II, PhD
West Virginia University

"Association of Germline Variants with Somatic TP53 and PIK3CA Mutations in Breast Cancer"
Amanda Toland, PhD
The Ohio State University

"Filament Formation by Metabolic Enzymes: A new twist on breast cancer metabolism"
Bradley Webb, PhD
West Virginia University

Q&A panel discussion

9:40-9:50 Break
9:50-10:50 Poster Session
10:50-11:00 Break
11:00am-12:00pm "Keynote Presentation: "Tackling Resistance in Triple-negative Breast Cancer"
Helen Piwnica-Worms, PhD
The University of Texas MD Anderson Cancer Center
12:00-12:30 Lunch
12:30-1:30 Patient Advocacy Session
1:30-1:40 Break
1:40-2:40 Poster Session
2:40-2:50 Break
2:50-4:25

SESSION V: Metastasis

"TNBC Signaling and Drug Response Dynamics in the Metastatic Niche"
Alexander Davies, DVM, PhD
The Ohio State University

"Neural Communication in Metastatic Progression"
Jennifer Yu, MD, PhD
Case Comprehensive Cancer Center, Cleveland Clinic

"Targeting MRTF Signaling to Disrupt Metastatic Colonization of Breast Cancer Cells"
Partha Roy, PhD
University of Pittsburgh

"Whole Transcriptome Profiling of Circulating Tumor Cells in Metastatic Breast Cancer"
Julie Lang, MD
Cleveland Clinic

Q&A panel discussion

4:25-4:35 Closing remarks