Cancer Genomics and Epigenomics | Case Comprehensive Cancer Center

The Cancer Genomics and Epigenomics (CGE) Program is the hub for cancer genome and epigenome discoveries and technology developments at our cancer center. The overarching goals of CGE are to discover the genetic and epigenetic alterations that contribute to cancer, to uncover the mechanisms by which these alterations form, and to translate these discoveries toward the prevention, diagnosis, and treatment of cancer.

Program Aims

Discover germline and somatic genetic alterations and elucidate the mechanisms by which these alterations drive tumorigenesis.
Discover novel epigenetic or epigenomic regulators of cancers.
Translate genetic and epigenetic discoveries for cancer diagnosis and therapy.

Program Members

Sara Akhavanfard, MD, PhD

Assistant Professor, Department of Pathology, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: sara.akhavanfard@case.edu

Phone: 216.983.1173
Joshua Arbesman, MD

Assistant Professor, Department of Dermatology, School of Medicine

Assistant Professor, Department of Medicine, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: arbesmj@ccf.org
Olumuyiwa Awoniyi, MD, PhD

Assistant Professor, Case Comprehensive Cancer Center, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: awoniyo@ccf.org
Andrew Blum, MD, PhD

Assistant Professor, Department of Medicine, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: andrew.blum@case.edu

Phone: 216.791.3800
G. Valentin Börner, PhD

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: g.boerner@csuohio.edu

Phone: 216.523.7557
Kaixiang Cao, PhD

Assistant Professor, Department of Biochemistry, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Assistant Professor, Department of Genetics and Genome Sciences, School of Medicine

Email: kxc725@case.edu

Phone: 216.368.1218
Amitabh Chak, MD

Professor, Department of Medicine, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: Amitabh.Chak@uhhospitals.org

Phone: 216.844.3217
Abhishek A. Chakraborty, PhD

Assistant Professor, Department of Molecular Medicine, School of Medicine

Co-Leader, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: chakraa@ccf.org

Phone: 216.445.6620
Yu-Wei Cheng, PhD

Laboratory Medicine, Cleveland Clinic

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: chengy@ccf.org

Phone: 216.445.0757
Ronald A. Conlon, PhD

Professor, Department of Genetics and Genome Sciences, School of Medicine

Director, Case Transgenic and Targeting Facility

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: ronald.conlon@case.edu

Phone: 216.368.1826
Josephine Kam Tai Dermawan, MD, PhD

Assistant Professor, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: dermawj@ccf.org
Andrew Dhawan, MD, PhD

Associate Staff, Cleveland Clinic

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: dhawana@ccf.org
Stephen P. Fink, PhD

Associate Professor, Case Comprehensive Cancer Center

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: stephen.fink@case.edu

Phone: 216.368.5657
Yuan Gao, PhD

Assistant Professor, Department of Pharmacology, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: yxg811@case.edu

Phone: 216.368.6632
Leah A. Gates, PhD

Assistant Professor, Department of Biochemistry, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: leah.gates@case.edu

Phone: 216-368-5572
Berkley Gryder, PhD

Assistant Professor, Department of Genetics and Genome Sciences, School of Medicine

Assistant Professor, Case Comprehensive Cancer Center, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Member, Angie Fowler Adolescent and Young Adult Cancer Research Initiative

Email: beg33@case.edu

Phone: 216.368.8749
Kishore Guda, DVM, PhD

Associate Professor, Digestive Health Research Institute, School of Medicine

Associate Professor, Case Comprehensive Cancer Center

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: gkishore@yahoo.com

Phone: 216.368.5665
Xiaonan Han, PhD

Associate Professor, Department of Hematology and Oncology, MetroHealth Medical Center

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: xxh455@case.edu

Phone: 216-778-8968
Ann Harris, PhD

Professor, Department of Genetics and Genome Sciences, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: ann.harris@case.edu

Phone: 216.368.6651
Peter J. Harte, PhD

Professor, Department of Genetics and Genome Sciences, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: peter.harte@case.edu

Phone: 216.368.6417
Ming Hu, PhD

Associate Professor, Department of Medicine, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: hum@ccf.org

Phone: 216.445.5057
Sudha K. Iyengar, PhD

Professor and Vice Chair for Research, Department of Population and Quantitative Health Sciences, School of Medicine

Frederick C. Robbins, M.D. Professor in Child and Adolescent Health, Department of Population and Quantitative Health Sciences, School of Medicine

Professor, Department of Genetics and Genome Sciences, School of Medicine

Professor, Department of Ophthalmology and Visual Sciences, School of Medicine

Faculty, Cleveland Institute for Computational Biology, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: sudha.iyengar@case.edu

Phone: 216.368.4388
Fulai Jin, PhD

Professor, Department of Genetics and Genome Sciences, School of Medicine

Associate Professor, Department of Population and Quantitative Health Sciences, School of Medicine

Associate Professor, Department of Computer and Data Sciences, Case School of Engineering

Co-Leader, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: fulai.jin@case.edu

Phone: 216.368.1811
Jae Jung, PhD

Special Advisor to the Director, Case Comprehensive Cancer Center

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: jungj@ccf.org
Tae Hun Kim, PhD

Assistant Professor, Department of Biochemistry, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: txk560@case.edu

Phone: 216.368.1857
Mehmet Koyutürk, PhD

Andrew R. Jennings Professor, Department of Computer and Data Sciences, Case School of Engineering

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: mehmet.koyuturk@case.edu

Phone: 216.368.2963
Thomas LaFramboise, PhD

Professor, Department of Genetics and Genome Sciences, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: thomas.laframboise@case.edu

Phone: 216.368.0150
Julie Lang, MD

Professor, Surgery, Lerner Research Institute, Cleveland Clinic

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: langj2@ccf.org
Fu-Sen Liang, PhD

Associate Professor, Department of Chemistry, College of Arts and Sciences

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Associate Professor, Department of Genetics and Genome Sciences, School of Medicine

Email: fxl240@case.edu

Phone: 216.368.3696
Joseph M. Luna, PhD

Assistant Professor, Department of Biochemistry, School of Medicine

Member, Center for RNA Science and Therapeutics, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Director, Advanced RNA Profiling Core

Email: joseph.luna@case.edu

Phone: 216.368.1119
Jaroslaw P. Maciejewski, MD, PhD

Professor, Department of Medicine, School of Medicine

Professor, Department of Pathology, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: maciejj@ccf.org

Phone: 216.445.5962
Sanford Markowitz, MD, PhD

Ingalls Professor of Cancer Genetics, Department of Medicine, School of Medicine

Professor, Department of Genetics and Genome Sciences, School of Medicine

Professor, Department of Molecular Biology and Microbiology, School of Medicine

Principal Investigator, Case GI SPORE, Case Comprehensive Cancer Center

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: sxm10@case.edu

Phone: 216-368-1976
Tyler E. Miller, MD, PhD

Assistant Professor, Department of Pathology, School of Medicine

Member, Immune Oncology Program, Case Comprehensive Cancer Center

Email: tymiller@case.edu

Phone: 216.286.2807
Jacob Miller, MD

Assistant Professor, Radiation Oncology, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: millerj73@ccf.org
Alexander Miron, PhD

Director, Genomics Core, School of Medicine

Associate Professor, Department of Genetics and Genome Sciences, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: alexander.miron@case.edu

Phone: 216.368.2791
Ying Ni, PhD

Assistant Professor, Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: niy@ccf.org
Tomas Radivoyevitch, PhD

Associate Professor, Department of Medicine, School of Medicine

Adjunct Assistant Professor, Department of Population and Quantitative Health Sciences, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: radivot@ccf.org

Phone: 216.442.5649
Brian P. Rubin, MD, PhD

Professor, Department of Pathology, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: rubinb2@ccf.org

Phone: 216.445.6953
Kurt W. Runge, PhD

Associate Professor, Department of Genetics and Genome Sciences, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: rungek@ccf.org

Phone: 216.445.9771
Helen Salz, PhD

Professor, Department of Genetics and Genome Sciences, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: helen.salz@case.edu

Phone: 216.368.2879
Richa Sharma, MD

Associate Staff, Pediatric Hematology Oncology, Cleveland Clinic

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: sharmar19@ccf.org
Rodrigo Somoza Palacios, PhD

Research Assistant Professor, Department of Biology, Case Western Reserve University

Director, Skeletal Research Center, Case Western Reserve University

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: ras286@case.edu
Paul J. Tesar, PhD

Director, Institute for Glial Sciences, School of Medicine

Professor, Department of Genetics and Genome Sciences, School of Medicine

Professor, Department of Neurosciences, School of Medicine

Dr. Donald and Ruth Weber Goodman Professor of Innovative Therapeutics, Department of Genetics and Genome Sciences, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: paul.tesar@case.edu

Phone: 216.368.6225
Zhenghe J Wang, PhD

Chair and Professor, Department of Genetics and Genome Sciences, School of Medicine

Dale H. Cowan M.D. – Ruth Goodman Blum Professor of Cancer Research

Co-Leader, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: zxw22@case.edu

Phone: 216.368.0446
Joseph Willis, MD

Professor, Department of Pathology, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center

Email: joseph.willis@case.edu

Phone: 216.844.8292
Chen-Han Wilfred Wu, MD, PhD

Assistant Professor, Department of Genetics and Genome Sciences, School of Medicine

Assistant Professor, Department of Urology, School of Medicine

Director, Urogenetics Program

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center, School of Medicine

Email: wilfred.wu@case.edu

Phone: 216.368.0837
Rong Xu, PhD

Professor of Biomedical Informatics, Director, Center for AI in Drug Discovery, School of Medicine

Member, Cancer Genomics and Epigenomics Program, Case Comprehensive Cancer Center, School of Medicine

Email: rxx@case.edu

Phone: 216.368.0023