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Cancer Genomics and Epigenomics

Program Information

The overarching goals of the Cancer Genomics (CG) Program are to discover the genetic and epigenetic alterations that contribute to cancer, to uncover the mechanisms by which these alterations form, and to translate these discoveries towards prevention, diagnosis, and treatment of cancer. 

Program Aims

  • Discover germline and somatic genetic alterations and elucidate the mechanisms by which these alterations drive tumorigenesis. 
  • Discover novel DNA methylations, histone modifications, DNA regulatory elements, 3-D chromosomal structures in cancers.
  • Translate genetic and epigenetic discoveries for cancer diagnosis and therapy. 

Program Members

  • Portrait of Joshua Arbesman

    Joshua Arbesman, MD

    Assistant Professor
    Department of Dermatology
    School of Medicine
    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: arbesmj@ccf.org

  • Andrew Blum 2023

    Andrew Blum, MD, PhD

    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: andrew.blum@case.edu

    Phone: 216.791.3800

  • Portrait of G. Valentin Böerner, PhD

    G. Valentin Böerner, PhD

    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: g.boerner@csuohio.edu

    Phone: 216.523.7557

  • Image of Henri Brunengraber

    Henri Brunengraber, MD, PhD

    Professor
    Department of Nutrition
    School of Medicine
    Professor
    Department of Biochemistry
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: henri.brunengraber@case.edu

    Phone: 216.368.6548

  • Dr. Kaixiang Cao

    Kaixiang Cao, PhD

    Assistant Professor
    Department of Biochemistry
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: kxc725@case.edu

    Phone: 216.368.1218

  • Portrait of Amitabh Chak, MD

    Amitabh Chak, MD

    Professor
    Department of Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: Amitabh.Chak@uhhospitals.org

    Phone: 216.844.3217

  • Portrait of Abhishek Chakraborty

    Abhishek A. Chakraborty, PhD

    Assistant Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: chakraa@ccf.org

    Phone: 216.445.6620

  • Ron Conlon

    Ronald A. Conlon, PhD

    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Director
    Case Transgenic and Targeting Facility
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: ronald.conlon@case.edu

    Phone: 216.368.1826

  • Portrait of Seth Corey

    Seth J. Corey, MD, MPH

    Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: coreys2@ccf.org

    Phone: 216.444.2506

  • Charis Eng

    Charis Eng, MD, PhD

    Professor and Vice Chair
    Department of Genetics and Genome Sciences
    School of Medicine
    Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: engc@ccf.org

    Phone: 216.444.3440

  • Portrait of Stephen Fink

    Stephen P. Fink, PhD

    Associate Professor
    Case Comprehensive Cancer Center
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: stephen.fink@case.edu

    Phone: 216.368.5657

  • Head shot of Berkley Gryder

    Berkley Gryder, PhD

    Assistant Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Assistant Professor
    Case Comprehensive Cancer Center
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center
    Member
    Angie Fowler Adolescent and Young Adult Cancer Research Initiative

    Email: berkley.gryder@case.edu

    Phone: 216.368.8749

  • Portrait of Kishore Guda

    Kishore Guda, DVM, PhD

    Associate Professor
    Case Comprehensive Cancer Center
    Associate Professor
    Digestive Health Research Institute
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: gkishore@yahoo.com

    Phone: 216.368.5665

  • Xiaonan Han, PhD

    Xiaonan Han, PhD

    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center
    Associate Professor
    Department of Hematology and Oncology
    MetroHealth Medical Center

    Email: xxh455@case.edu

    Phone: 216-778-8968

  • Image of headshot of Ann Harris

    Ann Harris, PhD

    Vice Chair of Research
    Department of Genetics and Genome Sciences
    School of Medicine
    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: ann.harris@case.edu

    Phone: 216.368.6651

  • Image of headshot of Peter Harte

    Peter J. Harte, PhD

    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: peter.harte@case.edu

    Phone: 216.368.6417

  • Headshot of Ming Hu. Man wearing glasses in a dark suit, blue dress shirt and striped tie.

    Ming Hu, PhD

    Associate Professor
    Department of Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: hum@ccf.org

    Phone: 216.445.5057

  • Image of headshot of Sudha K. Iyengar

    Sudha K. Iyengar, PhD

    Professor and Vice Chair for Research
    Department of Population and Quantitative Health Sciences
    School of Medicine
    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Professor
    Department of Ophthalmology and Visual Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: sudha.iyengar@case.edu

    Phone: 216.368.4388

  • Head Shot of Fulai Jin

    Fulai Jin, PhD

    Associate Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Associate Professor
    Department of Computer and Data Sciences
    Case School of Engineering
    Co-Leader
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: fulai.jin@case.edu

    Phone: 216.368.1811

  • Portrait of Jae Jung

    Jae Jung, PhD

    Special Advisor to the Director
    Case Comprehensive Cancer Center
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: jungj@ccf.org

  • Portrait of Mehmet Koyuturk

    Mehmet Koyutürk, PhD

    Professor
    Department of Electrical Engineering and Computer Science
    Case School of Engineering
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: mxk331@case.edu

    Phone: 216.368.2963

  • Headshot Thomas LaFramboise

    Thomas LaFramboise, PhD

    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: thomas.laframboise@case.edu

    Phone: 216.368.0150

  • Portrait of Dennis Lal

    Dennis Lal, PhD

    Assistant Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: lald@ccf.org

  • headshot of Julie Lang

    Julie Lang, MD

    Chief
    Breast Surgery
    Lerner Research Institute, Cleveland Clinic
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: langj2@ccf.org

  • Portrait of Fu-Sen Liang

    Fu-Sen Liang, PhD

    Assistant Professor
    Department of Chemistry
    College of Arts and Sciences
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: fxl240@case.edu

    Phone: 216.368.3696

  • Joseph Luna image

    Joseph M. Luna, PhD

    Assistant Professor
    Department of Biochemistry
    School of Medicine
    Member
    Center for RNA Science and Therapeutics
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: joseph.luna@case.edu

    Phone: 216.368.1119

  • Portrait of Jaroslaw Maciejewski

    Jaroslaw P. Maciejewski, MD, PhD

    Professor
    Department of Medicine
    School of Medicine
    Professor
    Department of Pathology
    School of Medicine
    Associate Director for Translational Research
    Case Comprehensive Cancer Center
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: maciejj@ccf.org

    Phone: 216.445.5962

  • Portrait of Sanford Markowitz

    Sanford Markowitz, MD, PhD

    Ingalls Professor of Cancer Genetics
    Department of Medicine
    School of Medicine
    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Professor
    Department of Molecular Biology and Microbiology
    School of Medicine
    Principal Investigator
    Case GI SPORE
    Case Comprehensive Cancer Center
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: sxm10@case.edu

    Phone: 216-368-1976

  • Headshot of Christopher McFarland

    Christopher McFarland, PhD

    Assistant Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Assistant Professor
    Case Comprehensive Cancer Center
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: christopher.mcfarland@case.edu

    Phone: 216.368.3286

  • Alexander Miron, PhD

    Alexander Miron, PhD

    Director
    Genomics Core
    School of Medicine
    Associate Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: alexander.miron@case.edu

    Phone: 216.368.2791

  • Richard A. Padgett

    Richard A. Padgett, PhD

    Professor
    Department of Molecular Medicine
    School of Medicine
    Professor
    Center for RNA Science and Therapeutics
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: padgetr@ccf.org

    Phone: 216.445.2692

  • Tomas Radivoyevitch

    Tomas Radivoyevitch, PhD

    Associate Professor
    Department of Medicine
    School of Medicine
    Adjunct Assistant Professor
    Department of Population and Quantitative Health Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: radivot@ccf.org

    Phone: 216.442.5649

  • Kurt Runge

    Kurt W. Runge, PhD

    Associate Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: rungek@ccf.org

    Phone: 216.445.9771

  • Head shot of Helen Salz

    Helen Salz, PhD

    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: helen.salz@case.edu

    Phone: 216.368.2879

  • Robert H. Silverman

    Robert H. Silverman , PhD

    Professor
    Department of Molecular Medicine
    School of Medicine
    Professor
    Department of Biochemistry
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: silverr@ccf.org

    Phone: 216.445.9650

  • Head shot of Paul Tesar

    Paul J. Tesar, PhD

    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Professor
    Department of Neurosciences
    School of Medicine
    Dr. Donald and Ruth Weber Goodman Professor of Innovative Therapeutics
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: paul.tesar@case.edu

    Phone: 216.368.6225

  • Portrait of Zhenghe John Wang

    Zhenghe J Wang, PhD

    Vice Chair for Faculty Development
    Department of Genetics and Genome Sciences
    School of Medicine
    Dale H. Cowan M.D. – Ruth Goodman Blum Professor of Cancer Research
    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Co-Leader
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: zhenghe.wang@case.edu

    Phone: 216.368.0446

  • Anthony Wynshaw-Boris, MD, PhD Professor of Genetics and Chair, Department of Genetics and Genome Sciences at Case Western Reserve University School of Medicine; Director of ICARE

    Anthony Wynshaw-Boris, MD, PhD

    Professor and Chair
    Department of Genetics and Genome Sciences
    School of Medicine
    James H. Jewell MD ’34 Professor of Genetics
    Department of Genetics and Genome Sciences
    School of Medicine
    Professor
    Department of Neurosciences
    School of Medicine
    Professor
    Department of Pediatrics
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: anthony.wynshaw-boris@case.edu

    Phone: 216.368.0581

  • Image of headshot of Rong Xu

    Rong Xu, PhD

    Professor of Biomedical Informatics, Director
    Center for AI in Drug Discovery
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center
    School of Medicine

    Email: rxx@case.edu

    Phone: 216.368.0023