1. Home
  2. Research
  3. Research Programs
  4. Cancer Genomics and Epigenomics

Cancer Genomics and Epigenomics

The Cancer Genomics and Epigenomics (CGE) Program is the hub for cancer genome and epigenome discoveries and technology developments at our cancer center. The overarching goals of CGE are to discover the genetic and epigenetic alterations that contribute to cancer, to uncover the mechanisms by which these alterations form, and to translate these discoveries toward the prevention, diagnosis, and treatment of cancer.

Program Aims

  • Discover germline and somatic genetic alterations and elucidate the mechanisms by which these alterations drive tumorigenesis. 
  • Discover novel epigenetic or epigenomic regulators of cancers.
  • Translate genetic and epigenetic discoveries for cancer diagnosis and therapy. 

Program Members

  • Portrait of Joshua Arbesman

    Joshua Arbesman, MD

    Assistant Professor
    Department of Dermatology
    School of Medicine
    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: arbesmj@ccf.org

  • Olumuyiwa Awoniyi headshot

    Olumuyiwa Awoniyi, MD, PhD

    Assistant Professor
    Case Comprehensive Cancer Center
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: awoniyo@ccf.org

  • Andrew Blum 2023

    Andrew Blum, MD, PhD

    Assistant Professor
    Department of Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: andrew.blum@case.edu

    Phone: 216.791.3800

  • Portrait of G. Valentin Böerner, PhD

    G. Valentin Börner, PhD

    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: g.boerner@csuohio.edu

    Phone: 216.523.7557

  • Dr. Kaixiang Cao

    Kaixiang Cao, PhD

    Assistant Professor
    Department of Biochemistry
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center
    Assistant Professor
    Department of Genetics and Genome Sciences
    School of Medicine

    Email: kxc725@case.edu

    Phone: 216.368.1218

  • Portrait of Amitabh Chak, MD

    Amitabh Chak, MD

    Professor
    Department of Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: Amitabh.Chak@uhhospitals.org

    Phone: 216.844.3217

  • Portrait of Abhishek Chakraborty

    Abhishek A. Chakraborty, PhD

    Assistant Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: chakraa@ccf.org

    Phone: 216.445.6620

  • Ron Conlon

    Ronald A. Conlon, PhD

    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Director
    Case Transgenic and Targeting Facility
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: ronald.conlon@case.edu

    Phone: 216.368.1826

  • Portrait of Seth Corey

    Seth Corey, MD, MPH

    Professor
    Department of Molecular Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: coreys2@ccf.org

    Phone: 216.444.2506

  • Josephine Kam Tai Dermawan headshot

    Josephine Kam Tai Dermawan, MD, PhD

    Assistant Professor
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: dermawj@ccf.org

  • Andrew Dhawan headshot

    Andrew Dhawan, MD, PhD

    Associate Staff
    Cleveland Clinic
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: dhawana@ccf.org

  • Portrait of Stephen Fink

    Stephen P. Fink, PhD

    Associate Professor
    Case Comprehensive Cancer Center
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: stephen.fink@case.edu

    Phone: 216.368.5657

  • Dr. Yuan Gao, Assistant Professor of the Pharmacology Dept.

    Yuan Gao, PhD

    Assistant Professor
    Department of Pharmacology
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: yxg811@case.edu

    Phone: 216.368.6632

  • portrait picture of leah gates

    Leah A. Gates, PhD

    Assistant Professor
    Department of Biochemistry
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: leah.gates@case.edu

    Phone: 216-368-5572

  • Head shot of Berkley Gryder

    Berkley Gryder, PhD

    Assistant Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Assistant Professor
    Case Comprehensive Cancer Center
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center
    Member
    Angie Fowler Adolescent and Young Adult Cancer Research Initiative

    Email: beg33@case.edu

    Phone: 216.368.8749

  • Portrait of Kishore Guda

    Kishore Guda, DVM, PhD

    Associate Professor
    Digestive Health Research Institute
    School of Medicine
    Associate Professor
    Case Comprehensive Cancer Center
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: gkishore@yahoo.com

    Phone: 216.368.5665

  • Xiaonan Han, PhD

    Xiaonan Han, PhD

    Associate Professor
    Department of Hematology and Oncology
    MetroHealth Medical Center
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: xxh455@case.edu

    Phone: 216-778-8968

  • Image of headshot of Ann Harris

    Ann Harris, PhD

    Vice Chair of Research
    Department of Genetics and Genome Sciences
    School of Medicine
    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: ann.harris@case.edu

    Phone: 216.368.6651

  • Image of headshot of Peter Harte

    Peter J. Harte, PhD

    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: peter.harte@case.edu

    Phone: 216.368.6417

  • Headshot of Ming Hu. Man wearing glasses in a dark suit, blue dress shirt and striped tie.

    Ming Hu, PhD

    Associate Professor
    Department of Medicine
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: hum@ccf.org

    Phone: 216.445.5057

  • Image of headshot of Sudha K. Iyengar

    Sudha K. Iyengar, PhD

    Professor and Vice Chair for Research
    Department of Population and Quantitative Health Sciences
    School of Medicine
    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Professor
    Department of Ophthalmology and Visual Sciences
    School of Medicine
    Faculty
    Cleveland Institute for Computational Biology
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: sudha.iyengar@case.edu

    Phone: 216.368.4388

  • Fulai Jin headshot

    Fulai Jin, PhD

    Associate Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Associate Professor
    Department of Population and Quantitative Health Sciences
    School of Medicine
    Associate Professor
    Department of Computer and Data Sciences
    Case School of Engineering
    Co-Leader
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: fulai.jin@case.edu

    Phone: 216.368.1811

  • Portrait of Jae Jung

    Jae Jung, PhD

    Special Advisor to the Director
    Case Comprehensive Cancer Center
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: jungj@ccf.org

  • Portrait picture of Tae Hun Kim

    Tae Hun Kim, PhD

    Assistant Professor
    Department of Biochemistry
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: txk560@case.edu

    Phone: 216.368.1857

  • Portrait of Mehmet Koyuturk

    Mehmet Koyutürk, PhD

    Andrew R. Jennings Professor
    Department of Computer and Data Sciences
    Case School of Engineering
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: mehmet.koyuturk@case.edu

    Phone: 216.368.2963

  • Headshot Thomas LaFramboise

    Thomas LaFramboise, PhD

    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: thomas.laframboise@case.edu

    Phone: 216.368.0150

  • headshot of Julie Lang

    Julie Lang, MD

    Professor
    Surgery
    Lerner Research Institute, Cleveland Clinic
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: langj2@ccf.org

  • Portrait of Fu-Sen Liang

    Fu-Sen Liang, PhD

    Associate Professor
    Department of Chemistry
    College of Arts and Sciences
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center
    Associate Professor
    Department of Genetics and Genome Sciences
    School of Medicine

    Email: fxl240@case.edu

    Phone: 216.368.3696

  • Joseph Luna image

    Joseph M. Luna, PhD

    Assistant Professor
    Department of Biochemistry
    School of Medicine
    Member
    Center for RNA Science and Therapeutics
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center
    Director
    Advanced RNA Profiling Core

    Email: joseph.luna@case.edu

    Phone: 216.368.1119

  • Portrait of Jaroslaw Maciejewski

    Jaroslaw P. Maciejewski, MD, PhD

    Professor
    Department of Medicine
    School of Medicine
    Professor
    Department of Pathology
    School of Medicine
    Associate Director for Translational Research
    Case Comprehensive Cancer Center
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: maciejj@ccf.org

    Phone: 216.445.5962

  • Portrait of Sanford Markowitz

    Sanford Markowitz, MD, PhD

    Ingalls Professor of Cancer Genetics
    Department of Medicine
    School of Medicine
    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Professor
    Department of Molecular Biology and Microbiology
    School of Medicine
    Principal Investigator
    Case GI SPORE
    Case Comprehensive Cancer Center
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: sxm10@case.edu

    Phone: 216-368-1976

  • Tyler Miller

    Tyler E. Miller, MD, PhD

    Assistant Professor
    Department of Pathology
    School of Medicine
    Member
    Immune Oncology Program
    Case Comprehensive Cancer Center

    Email: tymiller@case.edu

    Phone: 216.286.2807

  • Jacob Miller headshot

    Jacob Miller, MD

    Assistant Professor
    Radiation Oncology
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: millerj73@ccf.org

  • Alexander Miron, PhD

    Alexander Miron, PhD

    Director
    Genomics Core
    School of Medicine
    Associate Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: alexander.miron@case.edu

    Phone: 216.368.2791

  • Ying Ni headshot

    Ying Ni, PhD

    Assistant Professor
    Center for Immunotherapy and Precision Immuno-Oncology
    Cleveland Clinic
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: niy@ccf.org

  • Tomas Radivoyevitch

    Tomas Radivoyevitch, PhD

    Associate Professor
    Department of Medicine
    School of Medicine
    Adjunct Assistant Professor
    Department of Population and Quantitative Health Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: radivot@ccf.org

    Phone: 216.442.5649

  • Portrait of Brian Rubin

    Brian P. Rubin, MD, PhD

    Professor
    Department of Pathology
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: rubinb2@ccf.org

    Phone: 216.445.6953

  • Kurt Runge

    Kurt W. Runge, PhD

    Associate Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: rungek@ccf.org

    Phone: 216.445.9771

  • Head shot of Helen Salz

    Helen Salz, PhD

    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: helen.salz@case.edu

    Phone: 216.368.2879

  • Richa Sharma headshot

    Richa Sharma, MD

    Associate Staff
    Pediatric Hematology Oncology
    Cleveland Clinic
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: sharmar19@ccf.org

  • Image of headshot of Rodrigo Somoza

    Rodrigo Somoza Palacios, PhD

    Research Assistant Professor
    Department of Biology
    Case Western Reserve University
    Director
    Skeletal Research Center
    Case Western Reserve University
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: ras286@case.edu

  • Head shot of Paul Tesar

    Paul J. Tesar, PhD

    Director
    Institute for Glial Sciences
    School of Medicine
    Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Professor
    Department of Neurosciences
    School of Medicine
    Dr. Donald and Ruth Weber Goodman Professor of Innovative Therapeutics
    Department of Genetics and Genome Sciences
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: paul.tesar@case.edu

    Phone: 216.368.6225

  • John Wang headshot

    Zhenghe J Wang, PhD

    Chair and Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Dale H. Cowan M.D. – Ruth Goodman Blum Professor of Cancer Research
    Co-Leader
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: zxw22@case.edu

    Phone: 216.368.0446

  • Portrait of Joseph Willis

    Joseph Willis, MD

    Professor
    Department of Pathology
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center

    Email: joseph.willis@case.edu

    Phone: 216.844.8292

  • Headshot of Chen-Han Wilfred Wu

    Chen-Han Wilfred Wu, MD, PhD

    Assistant Professor
    Department of Genetics and Genome Sciences
    School of Medicine
    Assistant Professor
    Department of Urology
    School of Medicine
    Director
    Urogenetics Program
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center
    School of Medicine

    Email: wilfred.wu@case.edu

    Phone: 216.368.0837

  • Image of headshot of Rong Xu

    Rong Xu, PhD

    Professor of Biomedical Informatics, Director
    Center for AI in Drug Discovery
    School of Medicine
    Member
    Cancer Genomics and Epigenomics Program
    Case Comprehensive Cancer Center
    School of Medicine

    Email: rxx@case.edu

    Phone: 216.368.0023