The Clinical and Translational Science Collaborative (CTSC) of Cleveland, a collaborative among Case Western Reserve University (CWRU) and its affiliated hospital systems, the Cleveland Clinic (CC), MetroHealth (MH), University Hospitals (UH), and the Louis Stokes Veterans Administration Medical Center (VA) aspires to be a catalyst for high quality clinical and translational (C/T) research both locally and nationally by changing the culture and environment of biomedical research, sharing resources and expertise, and streamlining the research process to move translational research from bench to bedside and to the community.