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Institute for Transformative Molecular Medicine (ITMM)

The Institute for Transformative Molecular Medicine (ITMM)—supported by Case Western Reserve University School of Medicine and the Harrington Discovery Institute at University Hospitals—provides a fertile, resource-rich environment to enable transformative advances in medicine.

Under the direction of Distinguished University Professor Jonathan Stamler, MD, ITMM leverages its efforts to ignite interdisciplinary and to integrate humanity and technology through:

  • Members spanning all disciplines of medicine and biomedical research
  • Cutting-edge resources and a vibrant research environment
  • Infrastructure to support funding, performing and biomedical research reporting

Mission

ITMM's mission is to transform medicine through discovery of molecular mechanisms of disease to be leveraged toward therapeutic benefit.

Research

ITMM measures its success through:

  • High-profile manuscripts that report discoveries that meaningfully advance understanding of human health and disease
  • Movement of basic science discoveries into therapeutic development programs
  • Patents generated
  • Leadership in national and international initiatives to advance understanding of human health and to develop new therapeutics
  • Recognition by awards and honor societies, such as the American Society for Clinical Investigation, American Academy of Pediatrics and the National Academy of Medicine

Researchers

ITMM innovates traditional research models by committing to support members of Case Western Reserve University School of Medicine and the Harrington Discovery Institute at University Hospitals for unrestricted pursuit of knowledge for the sake of immediate human impact.

Primary Faculty

Jonathan Stamler, MD
Department of Cardiology

Seth Field, MD, PhD
Department of Endocrinology

Andrew Pieper, MD, PhD
Department of Psychiatry

Atul Chopra, PhD
Department of Medicine

Secondary Faculty

Richard Premont, PhD
Department of Medicine 

James Reynolds, PhD
Department of Anesthesiology and Perioperative Medicine

Hua-Lin Zhou, PhD
Department of Physiology and Biophysics

Puneet Seth, PhD
Department of Medicine

Alfred Hausladen, PhD
Department of Medicine

Matthew Wood, PhD
CWRU Department of Medicine; Oxford University Department of Pediatrics

Laurent Servais, PhD
CWRU Department of Medicine; Oxford University Department of Pediatrics

Carlo Rinaldi, PhD
CWRU Department of Medicine; Oxford University Department of Pediatrics