Shaking with Laughter

On Saturday, April 24, 2021, Case Western Reserve University School of Medicine hosted Shaking With Laughter to benefit Parkinson's disease research at CWRU School of Medicine, founder of the community-wide Cleveland Brain Health Initiative which brings together partner institutions devoted to finding new cures and ways to care for people suffering from brain-related diseases and disorders.

As a result of the success of the event and support from our sponsors, donors, and guests, we were able to raise over $85,000 to support CBHI through established partnerships with the Jaffe Armsden Butler Endowed Fund for Parkinson’s Disease, established by Catherine Armsden and the late Lewis Butler, in honor of Karen Jaffe and her relentless pursuit of a cure for Parkinson’s disease. In addition, event proceeds will support the Meisel Family Foundation Fund in Parkinson’s Disease Research, which was established to support a community-based collaboration between CWRU and InMotion, a local organization that helps people with Parkinson's disease feel better every day.

Learn more about the Cleveland Brain Health Initiative.

To support these efforts with a gift, contact Stacy J. Langenderfer, Senior Director of Development, Basic and Translational Sciences at


Headliner: Randy Rainbow

Randy Rainbow is an American comedian, actor, singer, writer and satirist best known for his popular series of musical parodies and political spoofs, which have garnered him international acclaim.

The influencer and Internet sensation’s viral comedy videos receive millions of views across all social media and digital platforms.

Learn more about Randy Rainbow.

Featured Performers

John Pizzarelli

John Pizzarelli is a world-renowned guitarist and singer who has been hailed by the Boston Globe for “reinvigorating the Great American Songbook and re-popularizing jazz.” The Toronto Star pegged him as “the genial genius of the guitar.” And the Seattle Times saluted him as “a rare entertainer of the old school.”

Visit John's website.

Wayne Cotter

Wayne Cotter is a veteran of the talk shows, having appeared dozens of times with both David Letterman and Jay Leno. A top nationally touring comedian, Wayne hosted the Fox Television Network series Comic Strip Live for many years, and has been nominated as “Best Standup Comedian” in the American Comedy Awards.

Visit Wayne's website.

Carmen Lynch

Carmen Lynch has been featured on a string of late night shows including The Tonight Show Starring Jimmy Fallon, The Late Show with David LettermanThe Late Show with Stephen Colbert, Conan, and The Late Late Show with Craig Ferguson. Carmen has appeared in numerous prime time shows including The Good Wife, Inside Amy Schumer, and This Week at the Comedy Cellar.

Visit Carmen's website.

Moody McCarthy

Moody McCarthy has performed on Jimmy Kimmel Live, Conan, and the Letterman Show.  He’s also been featured on America’s Got Talent and Last Comic Standing, but gets asked more about his House Hunters episode.

Visit Moody's website.

Tim Cavanagh

Tim Cavanagh is a favorite on the nationally syndicated BOB & TOM Show, Tim is a veteran headliner in comedy clubs across the country.

Visit Tim's website.

Marc Jaffe

Marc Jaffe is not only the founder of Shaking with Laughter he was also a comedy writer and performer for many years. Marc has written for many top comedians from Garry Shandling to Paul Reiser and for many television shows, most notably Seinfeld.

Sponsors and in-kind Donors

Thank you to our sponsors!


  • Case Western Reserve University School of Medicine


  • Leppo Rents
  • The Usual Suspects


  • Fran and Jules Belkin
  • Edward and Barbara Bell Family Foundation
  • The Frangos Group
  • Marc and Karen Jaffe
  • Harvey Kay and Lorelei Stein-Sapir
  • Dennis and Ginny Lehman and Family
  • Laura Ospanik and Stephen Robbins

Thank you to our in-kind donors!

  • Cleveland Guardians
  • Kendall-Jackson Wine estate and Gardens
  • Cleveland Marriott Downtown at Key Tower
  • Carla Tricarichi and David Fleshler