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Researchers identify set of patterns from CT scans to help predict patient’s response to chemotherapy

Researchers at the Center for Computational Imaging and Personalized Diagnostics (CCIPD) at Case Western Reserve University have used artificial intelligence (AI) to identify patterns on computed tomography (CT) scans that offer new promise for treating patients with small cell lung cancer.

Three years ago, an anonymous donor challenged Case Western Reserve supporters to help endow 10 professorships each at the university’s medical and engineering schools. 

By committing to half of the amount required ($1 million), donors would have the opportunity to name the professorship the gift helped create.

That effort went so well that last month President Eric W. Kaler announced the donor added another $10 million to the original $20 million commitment.

In a new review article, published today in The New England Journal of Medicine, researchers from University Hospitals (UH), Case Western Reserve University and Boston College discuss evidence linking pollution and cardiovascular disease. The research team highlights strategies for reducing individual exposure to pollution, and the importance of government-supported interventions encouraging clean energy.

In a ceremony Oct. 22, School of Medicine Dean Stan Gerson awarded Maria Hatzoglou the Case Medal for Excellence in Health Science Innovation. She was recognized with the highest honor bestowed by the school for her groundbreaking research, decades of service and for being a wonderful role model. 

The use of opioids, methamphetamines, cocaine and other stimulants is the second-most common cause of exposure to HIV among those in the United States diagnosed with the virus that causes AIDS.

Thanks to a new $16 million, five-year grant from the National Institute on Drug Abuse of the National Institutes of Health, Case Western Reserve is launching a multi-institutional research effort dedicated to deepening understanding of the relationship between substance use and HIV.

Company’s esophageal cancer prevention tests developed jointly by medical school faculty at Case Western Reserve University and University Hospitals 

Lucid Diagnostics Inc., a company that produces esophageal cancer tests based on Case Western Reserve University and University Hospitals research, has completed a $70 million initial public offering (IPO) on the Nasdaq Global Market; at the IPO price, the company’s estimated value would be $467 million.

An analysis of electronic health records of nearly 580,000 fully vaccinated people in the United States found that while the risk of SARS-CoV-2 breakthrough infection among those with substance-use disorders was low overall, it was higher for people who misuse substances such as alcohol, tobacco, marijuana and opioids.

The study, led by researchers at Case Western Reserve University and the National Institute on Drug Abuse (NIDA)—part of the National Institutes of Health—was published in World Psychiatry.

Matt Burdett, Jessica DeCaro, Maita Diaz and Lisa Tersigni have a few things in common. They not only consistently perform their job duties in an outstanding manner, but they steadily operate with an exemplary attitude. Because of this, the School of Medicine is proud to recognize them as this year’s winners of the school’s staff awards, the highest honor it bestows upon staff members. 

School of Medicine Dean Stan Gerson congratulated the recipients on receiving the well-deserved awards, and thanked them for their continued service to the school.

The ACHIEVE GreatER initiative part of multi-institution partnership among Case Western Reserve University, University Hospitals, Wayne State University and Cleveland Metropolitan Housing Authority to address health outcomes

Researchers at Case Western Reserve University School of Medicine and University Hospitals (UH) 

In June of 2011, Caitlyn Gillespie had a spinal fusion to fix the curvature of her spine due to scoliosis. She was terrified and in pain, but Gillespie remembers one nurse who went above and beyond to make sure she was recovering and was as comfortable as she could be.  

“She made me feel secure with my scar,” Gillespie explained. “We formed a deep connection because we both were spinal fusion patients. Anything I needed, she provided.”

Findings shed light on which tumors may respond better to immune checkpoint blockade therapy

Researchers from the Case Comprehensive Cancer Center uncovered the potentially important role of the protein-coding gene, MYO10, in tumor development and immune therapy response. Their findings were published on Sept. 15 in Science Advances.

More than $2 million in NIH funding supports analysis of enhanced massive genetics data sets  

An international team of researchers, co-led by Case Western Reserve University, has secured an additional $2 million from the National Institutes of Health (NIH) to advance genetic research in age-related macular degeneration (AMD), the leading cause of visual impairment or blindness in the elderly.

Sanjay Rajagopalan, a leading Cleveland cardiovascular physician scientist, has been awarded a $7.5 million federal grant to support research on how the environment affects human health, and especially Type 2 diabetes and cardiovascular disease.