Program Themes
- Utilize imaging agents to study cancer pathogenesis and develop cancer-targeting therapeutics
- Codify quantifiable imaging metrics to study cancer biology and improve cancer treatments
- Translate novel imaging methodologies to patient care
Program Information
The overarching goal of the Cancer Imaging Program is to utilize imaging for basic discoveries of carcinogenic mechanisms and therapeutic development that will translate into improved patient care.
To provide structure and promote cohesion within the larger program, investigators are organized into four scientific focus areas that address key questions in cancer research and reflect specific areas of expertise of the Program's membership.
- Imaging of the Tumor Microenvironment: This focus group engages members who study the cancer microenvironment with the goal of identifying new markers and paradigms for drug targeting or cancer detection. This includes development of tools to assess the extent of tumor cell migration into surrounding host tissues for clinical assessment of disease dissemination.
- Image-Guided Therapies: Members of this focus group develop novel approaches for monitoring cancer treatment and evaluating efficacy in vivo and ultimately in patients. These efforts range from clever utilization of conventional imaging tools for rapid clinical translation to developing targeted imaging agents and the tools for assessing drug delivery.
- Nanotechnology for Imaging and Drug Delivery: Members of this focus group develop nanodevices that impact many aspects of cancer imaging and treatment such as gene transfer and drug delivery. Efforts in this group include utilization of metallic nanoparticles to specifically deliver contrast agents to disease sites.
- Stem Cell Imaging: This focus group utilizes imaging approaches to study the biology of stem cells in vivo, for instance in the therapeutic setting, and to observe cancer stem cells. Members investigate the interactions between stem cells and their microenvironment and have developed imaging techniques to track stem cell homing, engraftment, proliferation, and differentiation.
Program Members
Eben Alsberg, PhD
Professor, Biomedical Engineering
eben.alsberg@case.edu
Norbert E. Avril, MD
Professor, Nuclear Medicine
norbert.avril@UHhospitals.org
Chaitra Badve, MD
Assistant Professor, Radiology
chaitra.badve@UHhospitals.org
James P. Basilion, PhD
Professor, Radiology
jxb206@case.edu
Susann M. Brady-Kalnay, PhD
Professor, Molecular Biology & Microbiology
smb4@case.edu
Samuel T. Chao, MD
Assistant Professor, Brain Tumor and Neuro-oncology Center
chaos@ccf.org
Valdir C. Colussi, PhD
Associate Professor, Medical Physics
valdir.colussi@UHhospitals.org
Frank DiFilippo, PhD
Associate Professor, Nuclear Medicine
difilif@ccf.org
Jennifer Dorth, MD
Assistant Professor, Radiation Oncology
jennifer.dorth@UHhospitals.org
Rodney J. Ellis, MD
Assistant Professor, Radiation Oncology
rodney.ellis@UHhospitals.org
Agata A. Exner, PhD
Associate Professor, Radiology
agata.exner@case.edu
Chris A. Flask, PhD
Associate Professor, Radiology, Biomedical Engineering, and Pediatrics
caf@case.edu
Mark A. Griswold, PhD
Professor, MRI
mag46@case.edu
Vikas Gulani, MD, PhD
Associate Professor, Assistant Professor
vikas@case.edu
James W. Jacobberger, PhD
Professor, General Medical Sciences (Oncology)
jwj@case.edu
Efstathios Karathanasis, PhD
Assistant Professor, Radiology
stathis@case.edu
Shlomo Koyfman, MD
Assistant Professor, Medicine
koyfmas@ccf.org
Vinod Labhasetwar, PhD
Professor, Biomedical Engineering
labhasv@ccf.org
Zhenghong Lee, PhD
Associate Professor, Radiology
zxl11@case.edu
Zheng-Rong Lu, PhD
Professor, Biomedical Engineering
zxl125@case.edu
Mitchell M. Machtay, MD
Professor, Radiation Oncology
mitchell.machtay@UHhospitals.org
Anant Madabhushi, MS, PhD
Professor, Biomedical Engineering
anant.madabhushi@case.edu
David Mansur, MD
Associate Professor, Radiation Oncology
david.mansur@UHhospitals.org
Gordon McLennan, MD
Professor, Diagnostic Radiology
mclenng@ccf.org
Raymond F. Muzic, Jr., PhD
Professor, Radiology
raymond.muzic@case.edu
Donna Plecha, MD
Associate Professor, Radiology
donna.plecha@UHhospitals.org
Tarun Podder, PhD
Associate Professor, Medical Physics
txp172@case.edu
Andrew M. Rollins, PhD
Associate Professor, Biomedical Engineering
amr9@case.edu
Pablo R. Ros, MD, MPH, PhD
Professor and Chair, Radiology
pablo.ros@UHhospitals.org
Robert G. Salomon, PhD
Professor, Chemistry
rgs@case.edu
Nicole Seiberlich, PhD
Assistant Professor, Biomedical Engineering
nes30@case.edu
Anirban Sen Gupta, PhD
Associate Professor, Biomedical Engineering
anirban.sengupta@case.edu
Andrew E. Sloan, MD
Professor, Neurological Surgery
andrew.sloan@UHhospitals.org
Nicole F. Steinmetz, PhD
Associate Professor, Biomedical Engineering
nicole.steinmetz@case.edu
Jeffrey L. Sunshine, MD, PhD
Professor, Radiology
jeffrey.sunshine@UHhospitals.org
Satish Viswanath, PhD
Assistant Professor, Biomedical Engineering
satish.viswanath@case.edu
Horst A. von Recum, PhD
Professor, Biomedical Engineering
horst.vonrecum@case.edu
Yanming Wang, PhD
Associate Professor, Radiology
yanming.wang@case.edu
David L. Wilson, PhD
Professor, Biomedical Engineering
dlw@case.edu
Min Yao, MD, PhD
Professor, Radiation Oncology
min.yao@UHhospitals.org